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EC number: 604-958-6
CAS number: 15448-47-2
Propylene oxide and/or its metabolites are readily absorbed through the
gastrointestinal and respiratory tracts and widely distributed to the
major organs. Studies in animals have suggested that clearance from the
blood may be limited at higher concentrations of exposure, indicating
saturation of metabolism. Metabolism involves conjugation with
glutathione or hydrolysis to epoxide hydrolase. Excretion of propylene
oxide and its metabolites is expected to be primarily via urine and
expired air. Propylene oxide binds to, or reacts with, tissues and
nucleic acids in vitro and in vivo.
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