Registration Dossier

Classification & Labelling & PBT assessment

DSD-DPD

General information

Name:
(R)-Propylene oxide
Status:
67/548/EEC self classification
Remarks:
Classification is based on the entry in Annex 1 for racemic methyloxirane (CAS 75-56-9, EC 200-879-2, Annex 1 Index Number 603-055-00-4). It is probable that, in the absence of data for this specific enantiomer, the chiral molecule has some or all of the properties of the racemic substance.

Classification

Explosiveness

Reason for no classification:
conclusive but not sufficient for classification

Oxidising properties

Reason for no classification:
conclusive but not sufficient for classification

Flammability

Classification:
F+; R12 Extremely flammable.

Thermal stability

Reason for no classification:
conclusive but not sufficient for classification

Acute toxicity

Classification:
Xn; R20/21/22 Harmful by inhalation, in contact with skin and if swallowed.

Acute toxicity - irreversible damage after single exposure

Reason for no classification:
conclusive but not sufficient for classification

Repeated dose toxicity

Reason for no classification:
conclusive but not sufficient for classification

Irritation / corrosion

Classification:
Xi; R36/37/38 Irritating to eyes, respiratory system and skin.

Sensitisation

Reason for no classification:
conclusive but not sufficient for classification

Carcinogenicity

Classification:
Carc. Cat. 2; R45 May cause cancer.

Mutagenicity - genetic toxicity

Classification:
Muta. Cat. 2; R46 May cause heritable genetic damage.

Toxicity to reproduction - fertility

Reason for no classification:
conclusive but not sufficient for classification

Toxicity to reproduction - development

Reason for no classification:
conclusive but not sufficient for classification

Toxicity to reproduction - breastfed babies

Reason for no classification:
conclusive but not sufficient for classification

Environment

Reason for no classification:
conclusive but not sufficient for classification

Labelling

Indication of danger

F+ - extremely flammable
T - toxic

Risk phrases

R12 - Extremely flammable
R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed
R36/37/38 - Irritating to eyes, respiratory system and skin
R45 - May cause cancer
R46 - May cause heritable genetic damage

Safety phrases

S53 - avoid exposure - obtain special instructions before use
S45 - in case of accident or if you feel unwell, seek medical advice immediately (show the label where possible)

Specific concentration limits

Notes

Note E