Registration Dossier
Registration Dossier
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EC number: 412-050-4 | CAS number: 125109-85-5 FLORHYDRAL
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- other: Body responsible for the test
- Title:
- Unnamed
- Year:
- 1 993
- Report date:
- 1993
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: EC B.14(Ames test)
- GLP compliance:
- yes
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- β-methyl-3-(1-methylethyl)benzenepropanal
- EC Number:
- 412-050-4
- EC Name:
- β-methyl-3-(1-methylethyl)benzenepropanal
- Cas Number:
- 125109-85-5
- Molecular formula:
- C13H18O
- IUPAC Name:
- 3-[3-(propan-2-yl)phenyl]butanal
Constituent 1
Method
Species / strain
- Species / strain / cell type:
- other: S. typhimurium TA 98, TA 100, TA 1535, TA 1537 and TA 1538
- Metabolic activation:
- with
- Metabolic activation system:
- S9-Mix(rat liver cell fraction)
- Vehicle / solvent:
- Solvent: DMSO
Results and discussion
Test results
- Species / strain:
- other: S. typhimurium TA 98, TA 100, TA 1535, TA 1537 and TA 1538
- Metabolic activation:
- not specified
- Genotoxicity:
- not specified
- Cytotoxicity / choice of top concentrations:
- not specified
- Additional information on results:
- Observations:
No genetic activity of the test material in any of the assays. - Remarks on result:
- other: other: S9-Mix(rat liver cell fraction)
- Remarks:
- Migrated from field 'Test system'.
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative with metabolic activation
negative without metabolic activation
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