Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 200-296-3 | CAS number: 56-89-3
Genetic toxicity: in vivo
Administrative data
- Endpoint:
- genetic toxicity in vivo
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- L-Cystine does not need to be classified for genetic toxicity in vitro. The read-across is justified due to the rapid conversion of L-Cysteine to L-Cystine and due to the fact that in many proteins two molecules of L-Cysteine form a disulfide bridge resulting in L-Cysteine. The mechanisms are described in detail in other sections of this CSR.
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Data source
Materials and methods
Results and discussion
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
