Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 223-829-1 | CAS number: 4090-51-1
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
In a reliable (reliability category 1) earthworm reproduction test performed compliant to GLP no statistically significant effects on mortality, biomass or reproduction of Eisenia fetida were observed up to the highest tested concentration. Thus, no EC10 or EC50 could be determined and the NOEC (56 d; mortality, biomass, reproduction) is larger or equal to 1000 mg/kg soil dw.
Key value for chemical safety assessment
Additional information
To assess possible terrestrial toxicity of the submission substance, chronic effects on mortality, biomass and the reproductive potential of the earthworm species Eisenia fetida (Savigny) were determined in a 8-week study compliant to GLP according to OECD 222 (2004; RL 1). In a static design, 5 concentrations (62.5 to 1000 mg/kg soil dw) with 4 replicates, each, together with 8 control replicates were assessed. The sexually mature earthworms had an initial individual body weight ranging between 0.30 and 0.52 g. Overall, the NOEC of the submission substance concerning mortality, biomass and reproduction of earthworms was determined to be equal or larger than 1000 mg/kg soil dry weight. All validity criteria recommended by the test guidelines were fulfilled.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
