Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 223-829-1 | CAS number: 4090-51-1
Endpoint summary
Administrative data
Description of key information
Additional information
The submission substance was assessed for possible aquatic toxicity in reliable tests (all reliability category 1) on freshwater algae (Scenedesmus subspicatus), freshwater invertebrates (Daphnia magna, acute), freshwater fish (zebra fish, acute) and sewage treatment plant microorganisms (activated sludge respiration inhibition test, 3 hours). In all these tests, nominal limit concentrations far above the actual water solubility of the submission substance were used (77 or 1000 mg/L). However, no signs of toxicity were observed in any of these tests. Thus, judging from these results terrestrial toxicity of the submission substance is unlikely. To ascertain this and in line with REACH guidance R.7c, chapter R.7.11.5, a possible chronic toxicity of the submission substance on earthworm reproduction was assessed. In the reliable (reliability category 1) test performed compliant to GLP no statistically significant effects on mortality, biomass or reproduction of Eisenia fetida were observed up to the highest tested concentration. Thus, the NOEC (56 d; mortality, biomass, reproduction) was determined to be larger or equal to 1000 mg/kg soil dw. In conclusion, taking together nontoxic properties of the submission substance towards aquatic (micro)organisms as well as soil macroorganisms (chronic test), toxicity of the submission substance towards terrestrial organisms can safely be precluded.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
