Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 201-961-0 | CAS number: 90-02-8
Eye irritation
Administrative data
- Endpoint:
- eye irritation
- Remarks:
- other: read across from analogy
- Type of information:
- migrated information: read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: The target chemical should be classified as Aldehyde AND Aryl by Organic Functional groups (extended)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guideline
- Guideline:
- other: read-across by QSAR toolbox
- GLP compliance:
- no
Test material
- Reference substance name:
- Salicylaldehyde
- EC Number:
- 201-961-0
- EC Name:
- Salicylaldehyde
- Cas Number:
- 90-02-8
- Molecular formula:
- C7H6O2
- IUPAC Name:
- 2-hydroxybenzaldehyde
- Reference substance name:
- 4-(methylthio)benzaldehyde
- EC Number:
- 222-365-7
- EC Name:
- 4-(methylthio)benzaldehyde
- Cas Number:
- 3446-89-7
- IUPAC Name:
- 4-(methylsulfanyl)benzaldehyde
- Reference substance name:
- 4-formylbenzoic acid
- EC Number:
- 210-607-4
- EC Name:
- 4-formylbenzoic acid
- Cas Number:
- 619-66-9
- IUPAC Name:
- 4-formylbenzoic acid
- Details on test material:
- CAS number:3446-89-7
Chemical name(s):4-(methylsulfanyl)benzaldehyde
CAS number: 619-66-9
Chemical name(s): 4-formylbenzoic acid
Constituent 1
Constituent 2
Constituent 3
Test animals / tissue source
- Species:
- rabbit
Results and discussion
In vivo
Results
- Irritation parameter:
- other: MMAS
- Time point:
- other: 3d
- Score:
- ca. 25
- Reversibility:
- not specified
Applicant's summary and conclusion
- Interpretation of results:
- not irritating
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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