Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin sensitisation

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Administrative data

Endpoint:
skin sensitisation
Remarks:
in vivo
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
1936
Report date:
1936

Materials and methods

In vivo test system

Test animals

Species:
guinea pig

Results and discussion

Applicant's summary and conclusion

Conclusions:
4-Chlorobenzoyl chloride may cause an allergic skin reaction.
Executive summary:

The test showed clear evidence for sensitization. This is also in accordance with the results of Toxtree QSAR.