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EC number: 205-031-5
CAS number: 131-57-7
This experiment was performed to assess the potential
of acute toxicty with test article at dose levels of 50, 100, 200, 400,
800, 1600 mg/kg. The NMRI mice were exposed via intraperitoneal
injection. For up to one hour after the application, all mice showed
sluggishness or sleepiness. There was no significant difference during
test period in all animals.One male animal died 11 days after the
injection of 800 mg/kg. For the animals sacrificed at the end of the
trial, 24 showed pale liver on macroscopic examination, and all the
other animals were unremarkable.
In conclusion, test article presented relatively low
toxicity on mice according to the experimental results, and LD50 can be
considered to be greater than 1600 mg/kg.
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