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Environmental fate & pathways

Biodegradation in water: screening tests

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Administrative data

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Description of key information

The substance is partly/moderately biodegradable, but not readily biodegradable according to OECD criteria.

Key value for chemical safety assessment

Additional information

The biodegradation of 2-Ethylhexylchloride (CAS 123 -04 -6) was tested in a GLP guideline study according to OECD 310 using activated sludge from a municipal sewage plant. The degree of biodegradation of 2-Ethylhexylchloride in the Carbon Dioxide Headspace Test was partly or moderately biodegradable based on the quantitative determination of the formed total inorganic carbon (TIC) in comparison to the applied amount of total organic carbon (TOC). The required pass level of biodegradation of 60% TIC/TOC at the end of exposure was not fulfilled. The degree of biodegradation after an exposure period of 60 days was 43 ± 4 % TIC/TOC in this test. In an OECD 301 B test, performed by Evonik Degussa GmbH (2003), no biodegradation was observed after 29d (3% CO2 evolution). This results supports the assumption the substance to be not readily biodegradable according to OECD criteria.

The test results can be supported by the QSAR models EPI Suite v4.10 SRC BIOWIN v4.10 and CATALOGIC v5.11.5TB BOD 28 days MITI (OECD 301C) v06.07. According to the latter model, the predicted metabolites are readily biodegradable (BOD> 60%).

Taking all results into account, the test substance is expected to be not readily biodegradable.