Registration Dossier

Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

Administrative data

Endpoint:
stability in organic solvents and identity of relevant degradation products
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1989-09-13
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Non GLP, non guideline conform.
Cross-referenceopen allclose all
Reason / purpose:
reference to same study
Reason / purpose:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1989
Report Date:
1989

Materials and methods

Principles of method if other than guideline:
Measurement of the stability of the test substance in n-hexane
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
NA

Results and discussion

Test substance stable:
yes
Transformation products:
not measured

Any other information on results incl. tables

At 20°C and 35°C no degradation of the free base was observed. At 50°C only a very slight degradation rate of 0.02 % was detected. Duration of the test: 2 months.

Applicant's summary and conclusion

Conclusions:
The test substance is stable in n-hexane.
Executive summary:

No degradation of the test material after 2 months in hexane observed at 20°C and 35°C.

A very slight degradation seen at 50°C (0.02%).

The test substance is stable in n-hexane.