Registration Dossier
Registration Dossier
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EC number: 202-784-1 | CAS number: 99-75-2
Epidemiological data
Administrative data
- Endpoint:
- epidemiological data
- Type of information:
- other:
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Study period:
- 1962
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Secondary source
Data source
Referenceopen allclose all
- Reference Type:
- secondary source
- Title:
- IUCLID Dataset Substance ID: 99-75-2
- Author:
- IUCLID
- Year:
- 2 000
- Bibliographic source:
- http://esis.jrc.ec.europa.eu/ with reference to Montefibre S.p.A
- Report date:
- 2000
- Reference Type:
- secondary source
- Title:
- Fragrance raw materials monographs. Methyl p-toluate
- Author:
- Opdyke DLJ
- Year:
- 1 979
- Bibliographic source:
- Food and Cosmetics Toxicology, Vol. 17 Suppl. 183-184
- Report date:
- 1979
Materials and methods
- Study type:
- other: workplace experience, not further specified
- Endpoint addressed:
- repeated dose toxicity: inhalation
- Principles of method if other than guideline:
- Occupational health study
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methyl p-toluate
- EC Number:
- 202-784-1
- EC Name:
- Methyl p-toluate
- Cas Number:
- 99-75-2
- Molecular formula:
- C9H10O2
- IUPAC Name:
- methyl 4-methylbenzoate
- Test material form:
- other: vapour
- Details on test material:
- no data
Constituent 1
Method
- Details on study design:
- no data
- Exposure assessment:
- not specified
Results and discussion
- Results:
- Workers exposed to methyl-p-toluate, among other substances, were reported to have shown moderate leucocytosis at the extense of neutrophils in several cases
- Confounding factors:
- other, unknown substances
Applicant's summary and conclusion
- Conclusions:
- No definite conclusions can be drawn from this study due to the presence of other, unknown substances at the workplace.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
