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EC number: 930-993-4
CAS number: -
weights, feed consumption and weight gain were comparable to control. No
gross signs of adverse systemic effect due to the ingestion of the test
material were observed in any of the animals.
consumption was determined as follows:
mg/kg bw/day (control), 75.14 mg/kg bw/day (0.125%), 1250.79 mg/kg
observations of bladder and kidney pathology see chapter 7.5
sacrificed during the study due to physiological problems:
necropsy of one (succumbed on day 158 of study) out of three control
animal showed congested testes and the ductus deferens appeared
enlarged. One control animal succumbed on day 148 revealed severely
necropsy of the four animals in Group II (0.125%), which were sacrificed
on an unscheduled basis, revealed testes without pathological findings.
gross necropsy (160 days) the testes of the control group appeared
necropsy of the animals of Group II (0.125%) showed findings which were
generally unremarkable. One male animal with right testis approximately
1/3 the expected normal size was observed.
necropsy of the animals of Group III (2%) sacrificed at 160-days,
revealed no effects on the testes.
necropsy of the animals in Group I (controls) showed testes without
necropsy of the animals, of Group II ( 0.125%) showed findings which
were generally unremarkable (testes without findings).
necropsy of the animals of Group III (2%), showed findings which were
generally unremarkable; one animal had small seminal vesicles.
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