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Viscosity

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Endpoint:
viscosity
Type of information:
other: Expert statement
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Expert statement
Principles of method if other than guideline:
Overview of different determinations
GLP compliance:
no
Type of method:
other: Übbelohde viscosimeter (dynamic) compared to handbook data
Temp.:
other: 25.0°C
Parameter:
other: cP
Value:
18.4
Remarks on result:
other: 80 % w/w solution of lactic acid

Concentration: 88.6%. Result: 36.9 mP s at 25 °C

Conclusions:
The value found by PURAC at 80% and 25oC matches with the values reported in Holten (75.33% lactic acid at 25°C, 13.03 cP and 85.32% at 25°C, 28.5 cP). The values of 18.4 cP at 80% and 25oC and 36.9 cP at 88.6% and 25oC are relevant.
Executive summary:

In a PURAC internal report 2) the viscosity of lactic acid at various concentrations and temperatures is given. Measurement is done by Übbelohde viscosimeter. Temperatures varied between 25°C and 80°C, concentrations between 20% and 80%. An 80% solution has a viscosity of 18.4 cP at 25°C.

Endpoint:
viscosity
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Principles of method if other than guideline:
Method: other: not reported
GLP compliance:
no
Type of method:
other: Übbelohde viscosimeter
Temp.:
other: 25.0°C
Parameter:
other: cP
Value:
18.4
Remarks on result:
other: 80 % aqueous solution
Temp.:
other: 40.0
Parameter:
other: cP
Value:
9.4
Remarks on result:
other: 80 % aqueous solution
Temp.:
other: 60.0
Parameter:
other: cP
Value:
4.8
Remarks on result:
other: 80 % aqueous solution
Temp.:
other: 80.0
Parameter:
other: cP
Value:
2.9
Remarks on result:
other: 80 % aqueous solution
Conclusions:
Viscosity of lactic acid 80% solution is determined with 18.4 cP at 25°C.
Executive summary:

Viscosity was determined with 18.4 cP at 25°C.

Endpoint:
viscosity
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Expert statement
Justification for type of information:
This information is used in a read-across approach in the assessment of the target substance.

Reason / purpose:
read-across source
Principles of method if other than guideline:
Overview of different determinations
GLP compliance:
no
Temp.:
other: 25.0°C
Parameter:
other: cP
Value:
18.4
Remarks on result:
other: 80 % w/w solution of lactic acid

Concentration: 88.6%. Result: 36.9 mP s at 25 °C

Conclusions:
The value found by PURAC at 80% and 25oC matches with the values reported in Holten (75.33% lactic acid at 25°C, 13.03 cP and 85.32% at 25°C, 28.5 cP). The values of 18.4 cP at 80% and 25oC and 36.9 cP at 88.6% and 25oC are relevant.
Executive summary:

In a PURAC internal report 2) the viscosity of lactic acid at various concentrations and temperatures is given. Measurement is done by Übbelohde viscosimeter. Temperatures varied between 25°C and 80°C, concentrations between 20% and 80%. An 80% solution has a viscosity of 18.4 cP at 25°C.

This information is used in a read-across approach in the assessment of the target substance.

For details and justification of read-across please refer to the attached report in section 13 of IUCLID.

Endpoint:
viscosity
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Justification for type of information:
This information is used in a read-across approach in the assessment of the target substance.

Reason / purpose:
read-across source
Principles of method if other than guideline:
Method: other: not reported
GLP compliance:
no
Type of method:
other: Übbelohde viscosimeter
Temp.:
other: 25.0°C
Parameter:
other: cP
Value:
18.4
Remarks on result:
other: 80 % aqueous solution
Temp.:
other: 40.0
Parameter:
other: cP
Value:
9.4
Remarks on result:
other: 80 % aqueous solution
Temp.:
other: 60.0
Parameter:
other: cP
Value:
4.8
Remarks on result:
other: 80 % aqueous solution
Temp.:
other: 80.0
Parameter:
other: cP
Value:
2.9
Remarks on result:
other: 80 % aqueous solution
Conclusions:
Viscosity of lactic acid 80% solution is determined with 18.4 cP at 25°C.
Executive summary:

Viscosity was determined with 18.4 cP at 25°C.

This information is used in a read-across approach in the assessment of the target substance.

For details and justification of read-across please refer to the attached report in section 13 of IUCLID.

Endpoint:
viscosity
Type of information:
other: Handbook data
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Principles of method if other than guideline:
Data are reported from literature sources. No methods were specified.
GLP compliance:
no
Type of method:
other: not reported
Temp.:
other: 25.0°C
Parameter:
dynamic viscosity (in mPa s)
Value:
36.9
Conclusions:
At 25°C a lactic acid aqueous solution of 88.6 % w/w has a viscosity of 36.9 centipoise. Viscosity increases with increasing concentration and decreases with increasing temperature.
Executive summary:

At 25°C a lactic acid aqueous solution of 88.6 % w/w has a viscosity of 36.9 centipoise. Viscosity increases with increasing concentration and decreases with increasing temperature.

Description of key information

A 93% aqueous solution of lactic acid) is a viscous liquid; an 80% aqueous solution has a viscosity at 25°C of 18.4 cP.

Key value for chemical safety assessment

Viscosity:
0 mPa · s (dynamic)
at the temperature of:
25 °C

Additional information