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EC number: 603-094-7
CAS number: 125904-11-2
STATEMENT FOR JUSTIFICATION OF OMISSION OF STUDY
Name of substance: Benzene,
ethenyl, ar–bromo derivs
Omitted study:A14: Explosive properties
The explosive properties were predicted based structural
considerations rather than by formal testing using Method A14 of Council
Regulation (EC) No 440/2008.Screening procedures
represent an intelligent testing strategy (ITS) for explosive
properties. In accordance with the Guidance on information requirements
and chemical safety assessment, if ITS is applied correctly to the
explosive properties endpoint, only substances for which it is suspected
will give a positive result in one of the explosive properties tests
need to be tested.
The structure of the substance was assessed
for chemical groups that would imply explosive properties. Common
examples of such groups areacetylenic compounds, metal
acetylides, haloacetylene derivatives, diazo compounds, nitroso and
nitro compounds, acyl or alkyl nitrites and nitrates, 1,2-epoxides,
metal fulminates oraci-nitro salts, N-metal derivatives,
N-nitroso and N-nitro compounds, N-azolium nitroimidates, azo compounds,
arene diazoates, bis-arenediazo oxides and sulfides, triazines,
high-nitrogen compounds, peroxy compounds, metal peroxides, peroxoacids
salts, azides, arenediazonium oxides, diazonium sulfides and
derivatives, arenediazo aryl sulfides, halogen oxide and N-halogen
A review of the structure suggests that there are no chemical
groups present that would imply explosive properties.
Based on the known chemical and physical properties of the
substance and its chemical structure, a negative result is predicted for
the A14 Explosive Properties test of Council
Regulation (EC) No 440/2008.As such it is
considered justified to omit the test.
Bretherick (1999) Bretherick’s Handbook of
Chemical Reactive Hazards: An Indexed Guide to Published Data, 6th
Edition (2 volume set).
W. C. Lothrop and G. R. Handrick. “The relationship between
performance and constitution of pure organic explosive compounds.”Chemical
Reviews, 44:419–445, 1949.
Table R.7.1-28 of Chapter R.7a: Endpoint
specific guidance within ECHA REACH Guidance on Information Requirements
and Chemical Safety Assessment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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