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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Hydrolysis
Administrative data
Link to relevant study record(s)
- Endpoint:
- hydrolysis
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 31st Jan to 12th june 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: - Study generated according to generally valid and/or internationally accepted testing guidelines - Performed according to GLP - Test parameters based on specific testing guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 111 (Hydrolysis as a Function of pH)
- Deviations:
- no
- Principles of method if other than guideline:
- OECD Guideline for Testing of Chemicals No. 111, “Hydrolysis as a Function of pH; adopted April 13, 2004 (only at pH 4.0, pH 7.0 and pH 9.0).
EEC Directive 92/69, Section C.7, “Abiotic Degradation: Hydrolysis as a Function of pH”, L383 A, December 1992. - GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- Details on properties of test surrogate or analogue material (migrated information):
None - Radiolabelling:
- not specified
- Analytical monitoring:
- not specified
- Details on sampling:
- See below
- Buffers:
- Buffer pH 4, Biphthalate Baker Art. No. 5657
Buffer pH 7, Phosphate Baker Art. No. 5656
Buffer pH 9, Borate Baker Art. No. 7145
The buffer solutions were sterilized for 25 minutes in an autoclave prior to first use. Nitrogen was passed through the buffer solutions for 2 minutes except when freshly sterilized. - Details on test conditions:
- According to the OECD guidelines. However due to the very low solubility of the FP-100 the test was not completed
- Number of replicates:
- N/A
- Statistical methods:
- see report
- Preliminary study:
- See report
- Test performance:
- The solubility of FP-100 in the buffer solutions pH 4.0, pH 7.0 and pH 9.0 was very low. It was not possible to increase the solubihty of the test item with the use of different solubilizers (acetonitrile, dimethylsulfoxide and tetrahydrofuran). Peaks obtained, if any, were too small to allow quantification or even to follow a degradation curve.
According to the EEC Directive 92/69, Section C.7, the method is applicable only to water soluble substances. The test item shows no significant solubility in the different solvent systems. Therefore, no further testing could be performed with FP-100 at pH 4.0, pH 7.0 and pH 9.0.
The r2 fit was 0.9999 (optimum = 1.0000). This reflects the linearity of the HPLC-system within the calibration range of 0.948 µg/mI to 113.76 µg/mI of the test item. - Transformation products:
- not measured
- Remarks on result:
- not determinable
- Other kinetic parameters:
- N/A
- Details on results:
- N/A
- Validity criteria fulfilled:
- yes
- Remarks:
- Solubility too low for test to be completed
- Conclusions:
- Hydrolysis of FP-100 could not be determined due to its poor water solubility
Reference
Description of key information
FP-100 is poorly water soluble and its hydrolysis could not be determined
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1 yr
- at the temperature of:
- 20 °C
Additional information
Hydrolysis of FP-100 could not be determined due to its poor water solubility
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