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EC number: 422-460-5 | CAS number: 137234-87-8 UK-103,442
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From 1996-06-28 to 1996-07-26
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- Deviations:
- no
- GLP compliance:
- yes
- Specific details on test material used for the study:
- Batch No.: 950704
Purity: 95.7% - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- - Source of activated sludge: The aeration stage of the Anglian Water sewage treatment plant (Godmanchester) treating predominantly domestic sewage.
- Preparation of inoculum for exposure: The sample was allowed to settle for approximately 30 minutes and the supernatant filtered through Whatman GFA coarse filter paper (first 250 mL discarded). The filtrate was maintained under aeration and used within 24 hours of collection. - Duration of test (contact time):
- 28 d
- Initial conc.:
- 2 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: see "APPENDIX 1 Standard mineral medium" in attached background material
- Preparation:
The test and standard substances were dispersed directly in mineral medium without the aid of auxiliary solvents or dispersing agents to give the following series:
(a) Inoculated mineral medium.
(b) Test substance (2 mg/L).
(c) Sodium benzoate (3 mg/L).
(d) Test substance (2 mg/L) plus sodium benzoate (3 mg/L).
The stock mineral medium with activated sewage sludge filtrate (at the rate of 1 mL of inoculum per litre) was inoculated immediately prior to the preparation of series (a), (b), (c) and (d).
- Procedure:
Biochemical Oxygen Demand bottles (280 mL) of darkened glass, fitted with ground glass stoppers, were filled by siphon and firmly stoppered to exclude all air bubbles. Sufficient bottles were prepared in each test and control series to allow a single oxygen determination per bottle to be made at 0, 4, 7, 11, 14, 18, 21, 25 and 28 days (duplicate bottles at each sampling time). Sufficient bottles for series (d) were prepared to provide information on inhibitory effects on Days 0, 14 and 28 only.
The bottles were incubated in a water bath at 20 1°C until removed for measurement of dissolved oxygen concentration by means of a Yellow Springs BOD Meter (Model 59). - Reference substance:
- benzoic acid, sodium salt
- Parameter:
- % degradation (O2 consumption)
- Value:
- 4
- Sampling time:
- 4 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 5
- Sampling time:
- 7 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 3
- Sampling time:
- 11 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 3
- Sampling time:
- 14 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 11
- Sampling time:
- 18 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 14
- Sampling time:
- 21 d
- Parameter:
- % degradation (O2 consumption)
- Value:
- 5
- Sampling time:
- 25 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- 10
- Sampling time:
- 28 d
- Details on results:
- Cultures containing both test and standard substances combined showed an oxygen depletion value 6% lower than that anticipated on the basis of results from separate cultures at Day 14. Consequently the test item is not considered to have had an inhibitory effect on sewage bacteria under the conditions of this test.
Oxygen depletions in the inoculated control series were within the prescribed limits ( ≤1.5 mgO2/L after 28 days). - Results with reference substance:
- Sodium benzoate attained 86% biodegradation within 28 days.
- Validity criteria fulfilled:
- no
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test item attained 10% degradation after 28 days.
- Executive summary:
A study was performed to assess the ready biodegradability of test item in accordance with OECD 301 D.
Sealed bottles containing the test substance and inorganic mineral medium were inoculated with activated sewage sludge bacteria and incubated for up to 28 days at 20±1°C. On Days 0, 4, 7, 11, 14, 18, 21, 25 and 28 duplicate bottles were taken and dissolved oxygen measured electrochemically.
The test item attained only 10% biodegradation after 28 days and therefore may not be termed as readily biodegradable.
The test item was not found to be inhibitory to activated sewage sludge bacteria under the conditions of this test.
Reference
Description of key information
A study was performed to assess the ready biodegradability of test item in accordance with OECD 301 D.
The test item attained only 10% biodegradation after 28 days and therefore may not be termed as readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
- Type of water:
- freshwater
Additional information
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