Registration Dossier

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Study period:
109 days
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019
Report Date:
2019

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
Deviations:
no
GLP compliance:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)

Study design

Test type:
static
Total exposure duration:
72 h

Test conditions

Test temperature:
For Range finding test 22.1°C - 22.7°C
For definitive test = 22.0 °C - 22.4°C
pH:
8.0 - 8.2

Results and discussion

Effect concentrations
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
1.53 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Remarks on result:
other:

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The Growth Inhibition value i.e. EC50 value for Thioctamidoethyl Dimethylamine Maleate in fresh water unicellular green algae Pseudokirchneriella subcapitata at 72hrs exposure period is estimated to be greater than 1.53 mg/L. The Study is performed as per OECD Guideline for testing of Chemicals Section 2, No. 201