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Physical & Chemical properties

Density

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Reference
Endpoint:
relative density
Type of information:
experimental study
Adequacy of study:
key study
Study period:
01 August 2017 to 24 September 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.3 (Relative Density)
Version / remarks:
2008
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Version / remarks:
2012
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
pycnometer method
Key result
Type:
relative density
Density:
1.536 other: no dimension
Temp.:
20 °C
Remarks on result:
other:

TABLE - DENSITY AND RELATIVE DENSITY OF TEST ITEM

 

DENSITY AND RELATIVE DENSITY OF TEST ITEM

Parameter

Replications

R1

R2

R3

Mass of empty pyknometer (g)

23.4435

23.4279

17.8823

Mass of empty pyknometer +Lid (g)

29.0871

28.7141

23.2112

Mass of empty pyknometer +Lid + test item (g)

32.3158

31.6886

26.2586

Mass of empty pyknometer +Lid + test item wetting solution (g)

57.7653

56.6921

50.9746

Volume of wetting solution (mL)

25.4234

24.9778

24.6906

Mass of test item (g)

3.2287

2.9745

3.0474

Density of test item (g/cm3)

1.5274

1.5437

1.5356

Mean density of test item (g/cm3)

1.536

Mean density of test item (kg/m3)

1536

Density of standard water at 4°C

1.000

Relative density of test item(D204)

1.536

 

 

Conclusions:
The mean relative density of the reaction mass of cucurbit[6]uril, cucurbit[7]uril and cucurbit[8]uril was found to be 1.536 at 20 deg C using the pyknometer method.
Executive summary:

The purpose of this study was to determine the relative density of the reaction mass of cucurbit[6]uril, cucurbit[7]uril and cucurbit[8]uril. The study was performed in accordance with the OECD guideline 109 and Regulation (EC) 440/2008, Annex Part A test A3. The density, determined by the pyknometer method, of the solid test item at 20°C was 1536 kg/m3. The relative density (D204) was 1.536.

Description of key information

A GLP study was conducted to determine density and relative density for the reaction mass of cucurbit [6]uril, cucurbit[7]uril and cucurbit[8]uril in accordance with current OECD and EU testing guidelines, using the pyknometer method. The density of the solid test item was 1536 kg/m3at 20°C. The relative density(D204) was 1.536.

Key value for chemical safety assessment

Relative density at 20C:
1.536

Additional information