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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
07 March - 20 June 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report date:
2018

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
EC Number:
606-374-7
Cas Number:
197706-51-7
Molecular formula:
C11H11FO2
IUPAC Name:
(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
Test material form:
other: wax
Details on test material:
Physical state: wax form
Appearance: clear, viscous, wax
Specific details on test material used for the study:
- Batch n°: I16DB1993
- Analytical purity: 88.4% (technical document DS-TEC-128833)
- Expiration date: 03 October 2017 (retest date)
- Storage condition: at room temperature

Results and discussion

Boiling point
Key result
Boiling pt.:
285.4 °C
Atm. press.:
1 020 hPa
Decomposition:
no

Any other information on results incl. tables

The extrapolated onset of the peak between 200°C and 325°C obtained in the first experiment was 285.036°C. The similar value found in an earlier experiment (results were not used due to a lower sample amount used) demonstrated that boiling of the test item was the reason for the endothermic effect. After the experiment it was observed that the test item was evaporated from the sample container.

A further experiment was performed to determine the boiling temperature of the test item. Similar results were obtained. The extrapolated onset of the evaporation

peak was 285.792°C. After the experiment it was observed that the test item was evaporated from the sample container.

The boiling temperature was determined as the average boiling temperature obtained from two experiments (285.036°C; 285.792°C) and equals 285.4°C (558.6K).

Applicant's summary and conclusion

Conclusions:
The boiling temperature of JNJ-17337268-AAA (T001597) was determined at 285.4°C (558.6K) by using DSC.
The atmospheric pressure was 1020 ± 3 hPa.