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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
16 December 2014 to 05 February 2015
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. The substance is considered to be adequately characterised with its purity. Therefore full validation applies.
Qualifier:
according to
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes
Type of method:
differential scanning calorimetry
Specific details on test material used for the study:
- Storage condition of test material: In refrigerator (2-8°C) protected from light, container flushed with nitrogen
- Stability at higher temperatures: Yes, maximum temperature: 40°C, maximum duration: 10 days
Key result
Melting / freezing pt.:
< -80 °C

During cooling, no effects were observed which were due to crystallization of the test substance.

To further investigate the freezing temperature of the test substance, two samples were stored for 19 hours at -22.0 ± 0.2 °C and -81.9 ± 1.9 °C respectively. It was observed after storage that the test substance was a viscous liquid (-20 °C freezer) and a very viscous liquid (-80 °C freezer). According to this it was concluded that the melting temperature of the test substance is < -80 °C (< 193 K).

Conclusions:
No further testing is required (< -20°C).
Executive summary:

The freezing point of the test substance was determined, under GLP, according to OECD 102 / EU A1 guideline, using Differential Scanning Calorimetry method.

The substance was first cooled down to -90°C, then re-heated. Crystallization or melting were not observed in the experiments performed by the DSC. Therefore a confirmatory limit test was conducted, with a subsample placed overnight in a freezer at -20 °C and at -80 °C: the substance was more viscous, but still liquid.

The freezing temperature of test substance was then determined to be < -80 °C.

Description of key information

No freezing down to -80°C.

(no further testing is required)

Key value for chemical safety assessment

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. It is considered as a key study. The result being expressed as a limit value, it is not retained as key data (no "<" sign allowed in the key value box).