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Ecotoxicological information

Short-term toxicity to fish

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1998
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Version / remarks:
1992
Deviations:
no
GLP compliance:
yes
Analytical monitoring:
not specified
Vehicle:
not specified
Test organisms (species):
Oryzias latipes
Details on test organisms:
TEST ORGANISM
- Common name: medaka (rice fish)
- Strain: Oryzias latipes
Test type:
semi-static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h
Test temperature:
24 ± 1 ºC
Nominal and measured concentrations:
100 mg/L (nominal)
Details on test conditions:
TEST SYSTEM
- Material, size, headspace, fill volume: volume 5.0 L
- Aeration: no
- Renewal rate of test solution (frequency/flow rate): every 48 hours
- No. of organisms per vessel: 10 per concentration

OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: 16 hours light - 8 hours dark (room light)

EFFECT PARAMETERS MEASURED (with observation intervals if applicable): mortality
Reference substance (positive control):
not specified
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
>= 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Validity criteria fulfilled:
not specified
Conclusions:
The 96h-LC50 of the test item in fish is ≥ 100 mg/L.
Executive summary:

An acute fish toxicity test was conducted according to OECD 203, under GLP conditions. A limit test was performed under semi-static conditions (renewal rate 48h). 10 fish per concentration were exposed to 100 mg/L test item or the control for 96 h at 24 ± 1 ºC. The 96h-LC50 of the test item in rice fish (Oryzias latipes) was determined to be ≥ 100 mg/L, based on nominal concentration.

Description of key information

Key study. Test method according to OECD 203, GLP study. The 96h-LC50 of the test item in rice fish (Oryzias latipes) was determined to be ≥ 100 mg/L, based on nominal concentration.

Key value for chemical safety assessment

LC50 for freshwater fish:
100 mg/L

Additional information