Registration Dossier

Toxicological information

Acute Toxicity: inhalation

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Administrative data

Endpoint:
acute toxicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1980
Report Date:
1980

Materials and methods

Principles of method if other than guideline:
Method: other: BASF test
GLP compliance:
no
Test type:
other: inhalation risk test (IRT)
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Test animals

Species:
rat
Strain:
not specified
Sex:
male/female

Administration / exposure

Route of administration:
inhalation: vapour
Type of inhalation exposure:
whole body
Vehicle:
air
Analytical verification of test atmosphere concentrations:
no
Duration of exposure:
7 h
Concentrations:
saturated atmosphere (20°C); max 0.85 mg/l
No. of animals per sex per dose:
a total of 12 animals
Control animals:
no

Results and discussion

Effect levels
Key result
Sex:
male/female
Dose descriptor:
LC50
Effect level:
> 0.85 mg/L air
Based on:
other: saturated atmosphere of the test item

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Executive summary:
No mortality was observed when 12 rats were exposed for 7 h to an atmosphere that has been saturated at 20°C with the volatile part of the compound.