Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-200-7
CAS number: -
In a GLP-compliant OECD Guideline 406 study,
skin sensitisation properties of multiconstituent aluminium potassium
fluoride were studied in guinea pig.
Test substance concentrations selected for
the main study were based on the results of a preliminary study. In the
main study, ten experimental animals were intradermally injected with a
2% concentration and epidermally exposed to a 50% concentration. Five
control animals were similarly treated, but with the vehicle (1% aqueous
carboxymethyl cellulose) only. Approximately 24 hours before the
epidermal induction exposure all animals were treated with 10% SDS. Two
weeks after epidermal application all animals were challenged with a 50%
test substance concentration an the vehicle.
No evidence was obtained that the test
substance had caused skin hypersensitivity in the guinea pig, since no
responses were observed in the experimental animals in the challenge
phase. This result indicates a sensitization rate of 0 per cent.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again