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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

Currently viewing:

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data

Data source

Reference
Reference Type:
publication
Title:
Range finding toxicity data: List VI
Author:
Smyth HF et al
Year:
1962
Bibliographic source:
Am Ind Hyg. Assoc J 23:95-107

Materials and methods

Test guideline
Qualifier:
no guideline available
Principles of method if other than guideline:
The study was reported in a collection of published data
GLP compliance:
no
Remarks:
collection of data published
Test type:
standard acute method
Limit test:
no

Test material

1
Chemical structure
Reference substance name:
1,3-dichloropropan-2-ol
EC Number:
202-491-9
EC Name:
1,3-dichloropropan-2-ol
Cas Number:
96-23-1
Molecular formula:
C3H6Cl2O
IUPAC Name:
1,3-dichloropropan-2-ol
Test material form:
liquid

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Type of coverage:
not specified
Vehicle:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 800 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
Category 3 based on GHS criteria
Conclusions:
The results of the study indicate that classification as Acute toxicity Category 3 may be justified- the European Commission has assigned a harmonised classification of Acute toxicity (dermal) category 4