Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 500-092-7 | CAS number: 36890-68-3
Endpoint summary
Administrative data
Description of key information
Reliable toxicity studies with freshwater fish, aquatic invertebrates and algae have been conducted for the test substance, ε-Caprolactone, oligomeric reaction products with 2,2’-oxydiethanol.
The key studies are summarised below:
A reliable (Klimisch 2) acute toxicity study with freshwater fish, Danio rerio (previously known as Brachydanio rerio) and using the test substance, ε-Caprolactone, oligomeric reaction products with 2,2’-oxydiethanol, is available with a 96-hour LC50 (mortality) of 190 mg/l, based on measured test concentrations. This value is taken as the short-term toxicity to fish endpoint for ε-Caprolactone, oligomeric reaction products with 2,2’-oxydiethanol.
A reliable (Klimisch 1) acute toxicity study with the aquatic invertebrate Daphnia magna and using the test substance, ε-Caprolactone, oligomeric reaction products with 2,2’-oxydiethanol is available with 48-hour EC50s of >105.8 mg/l and >94.6 mg/l based on geometric mean measured concentrations of two components of ε-Caprolactone, oligomeric reaction products with 2,2’-oxydiethanol. These values are taken as the short-term toxicity to aquatic invertebrates endpoint for ε-Caprolactone, oligomeric reaction products with 2,2’-oxydiethanol.
A reliable (Klimisch 1) study with the freshwater alga, Desmodesmus subspicatus, and using the test substance ε-Caprolactone, oligomeric reaction products with 2,2’-oxydiethanol is available with 72-hour ErC50 (growth rate inhibition) of 33.14 mg/l and 6.29 mg/l based on geometric mean measured concentrations of two components of the test substance. These values are taken as the toxicity in aquatic algae endpoint for ε-Caprolactone, oligomeric reaction products with 2,2’-oxydiethanol.
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
