Registration Dossier

Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2019

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 203 (Fish, Acute Toxicity Test)
Deviations:
no
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
liquid

Sampling and analysis

Analytical monitoring:
yes
Remarks:
ICP/OES

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
static
Water media type:
other: ultrapure
Limit test:
yes
Total exposure duration:
96 h

Test conditions

Hardness:
250 mg/L of CaCO3
Test temperature:
22.7 to 23.0°C
pH:
7.9
Dissolved oxygen:
9.1 mg/L
Nominal and measured concentrations:
100 mg/L
Reference substance (positive control):
yes
Remarks:
potassium dichromate

Results and discussion

Effect concentrations
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Results with reference substance (positive control):
The toxic response obtained on the reference item K2Cr2O7 for the Fish batch number 280818 gives a LC50-24h of 202.4 mg/L [176.7 – 233.0], in accordance with historical data obtained by the laboratory.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The results obtained for the test item « W3803S04SOLSIV» on the toxicological endpoint “mortality” give a LC50-96h higher than 100 mg/L (highest tested concentration), value expressed in nominal test item concentration.