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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
19.07.2017 - 04.10.2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
GLP compliance:
no
Type of method:
differential scanning calorimetry
Key result
Melting / freezing pt.:
117.1 °C
Atm. press.:
1 013 hPa
Decomposition:
no
Sublimation:
no

Two DSC measurements with a heating rate of 10 K/min showed an endothermal effect in the temperature range of 110 - 130 °C. The first measurement ending at 500 °C showed a second endothermal effect in the temperature range of 250 - 310 °C. The onset temperature was derived from the intersection of the tangent line with the highest slope of the endothermal peak with the baseline.

Table 1: Melting point (DSC measurements)

idem No.

Test item / mg

Starting temperature / °C

Final test temperature / °C

Temperature range (endo-thermal) / °C

Onset (melting) / °C

Crucible

Observations after the measurement

36397

10.96

25

500

110 – 130

250 - 310

117.9

n.r.

Aluminium with a hole

Black residue in crucible. Mass loss 53 %

36399

10.46

25

180

110-130

116.2

Aluminium with a hole

Test item was a white, solidified melt

n.r.: not relevant

Since in the second measurement ending at 180 °C a solidified melt was observed after the measurement, the first endotherm effect with an onset temperature of 117.9 °C can be assigned to the melting point of the test item. The test item had a mean melting point of 117.1 °C.

Conclusions:
The melting point of the test substance was determined to be 117 °C.
Executive summary:

A study was conducted according to OECD TG 102 and Regulation (EC) No 440/2008 method A.1 to determine the melting point of the test item using differential scanning calorimetry. The test item and the reference were heated up from the starting temperature to the final temperature at a constant heating rate in a defined atmosphere (nitrogen). Aluminium crucibles with hole were used as containers for the test item and the reference. Two DSC measurements with a heating rate of 10 K/min showed an endothermal effect in the temperature range of 110 - 130 °C. The first measurement ending at 500 °C showed a second endothermal effect in the temperature range of 250 - 310 °C. Since in the second measurement ending at 180 °C a solidified melt was observed after the measurement, the first endotherm effect with an onset temperature of 117.9 °C can be assigned to the melting point of the test item. The test item had a mean melting point of 117.1 °C (1013 hPa).

Description of key information

The test item had a mean melting point of 117.1 °C (reference 4.2-1).

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
117.1 °C

Additional information

A study was conducted according to OECD TG 102 and Regulation (EC) No 440/2008 method A.1 to determine the melting point of the test item using differential scanning calorimetry. The test item and the reference were heated up from the starting temperature to the final temperature at a constant heating rate in a defined atmosphere (nitrogen). Aluminium crucibles with hole were used as containers for the test item and the reference. Two DSC measurements with a heating rate of 10 K/min showed an endothermal effect in the temperature range of 110 - 130 °C. The first measurement ending at 500 °C showed a second endothermal effect in the temperature range of 250 - 310 °C. Since in the second measurement ending at 180 °C a solidified melt was observed after the measurement, the first endotherm effect with an onset temperature of 117.9 °C can be assigned to the melting point of the test item. The test item had a mean melting point of 117.1 °C (1013 hPa) (reference 4.2-1).