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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 201 (Freshwater Alga and Cyanobacteria, Growth Inhibition Test)
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Test material form:
solid: particulate/powder

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
yes
Remarks:
ultrapure water
Details on test solutions:
a special solubilization protocol was carried out before the experimentation according to OECD n°23 guidance document on aquatic toxicity testing of difficult subtances and mixtures

Test organisms

Test organisms (species):
Pseudokirchneriella subcapitata (previous names: Raphidocelis subcapitata, Selenastrum capricornutum)

Study design

Test type:
semi-static
Water media type:
not specified
Limit test:
no
Total exposure duration:
72 h

Test conditions

Test temperature:
range of 21 to 24°C
Nominal and measured concentrations:
test concentration : control - 0.3 - 1 - 3.2 - 10 - 32 and 100 mg/L
Details on test conditions:
control : 6 biotioc replicates
each concentration : 3 replicates
Reference substance (positive control):
yes
Remarks:
potassium dichromate

Results and discussion

Effect concentrationsopen allclose all
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
4.86 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
growth rate
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 0.3 - < 1 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: yield inhibition
Details on results:
The validity criteria were successfully fulfilled.
Results with reference substance (positive control):
not specified

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The results obtained for Stiripentol Stade 1 are :
- EC50-72h = 4.86 mg/L based on growth rate
- EC50-72h = 0.3 to 1 mg/L based on yield inhibition
In regard to these results the test item can be classified in Category : Acute II.
Executive summary:

The acute toxicity on aquatic algae was performed according the OECD 201 guideline.

The results obtained for Stiripentol Stade 1 are :

- EC50-72h = 4.86 mg/L based on growth rate

- EC50-72h = 0.3 to 1 mg/L based on yield inhibition

In regard to these results the test item can be classified in Category : Acute II.