Registration Dossier
Registration Dossier
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EC number: 239-827-9 | CAS number: 15733-89-8
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin corrosion: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 431 (In Vitro Skin Corrosion: Reconstructed Human Epidermis (RHE) Test Method)
- GLP compliance:
- yes
Test material
- Reference substance name:
- 1,2-dihydro-2-oxoquinoline-4-carboxylic acid
- EC Number:
- 239-827-9
- EC Name:
- 1,2-dihydro-2-oxoquinoline-4-carboxylic acid
- Cas Number:
- 15733-89-8
- Molecular formula:
- C10H7NO3
- IUPAC Name:
- 1,2-dihydro-2-oxoquinoline-4-carboxylic acid
- Test material form:
- solid: particulate/powder
Constituent 1
In vitro test system
- Test system:
- human skin model
- Control samples:
- yes, concurrent negative control
- yes, concurrent positive control
Results and discussion
In vitro
Results
- Irritation / corrosion parameter:
- % tissue viability
- Value:
- 107
- Negative controls validity:
- valid
- Positive controls validity:
- valid
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- In this in vitro EPISKIN™ (SM) model (OECD431 method) test with ACIDE HYDROXY, the results indicate that the test item is non-corrosive to the skin.
- Executive summary:
In this in vitro EPISKIN™ (SM) model (OECD431 method) test with ACIDE HYDROXY, the results indicate that the test item is non-corrosive to the skin.
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