Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Start of study 2012-01-25. Test phase 2012-02-07 to 2012-04-04. Report complete 2012-05-11.
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Meets the criteria for classification as reliable without restriction according to Klimisch et al (1997).

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes
Type of method:
column elution method

Test material

Constituent 1
Chemical structure
Reference substance name:
4-(naphthalen-2-yl)-1,3-thiazol-2-amine
EC Number:
606-740-6
Cas Number:
21331-43-1
Molecular formula:
C13H10N2S
IUPAC Name:
4-(naphthalen-2-yl)-1,3-thiazol-2-amine
Test material form:
solid: particulate/powder
Remarks:
migrated information: powder

Results and discussion

Water solubility
Water solubility:
3.2 mg/L
Temp.:
25 °C
pH:
6.62 - 7.31
Details on results:
Column Elution Run 1
Mean = 3.52 mg/l
Standard Deviation = 0.032%

Column Elution Run 2
Mean = 2.90 mg/l
Standard Deviation = 0.038%

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of the test material was determined to be 3.2 mg/L in this study. Therefore the test material is slightly soluble in water.
Executive summary:

Introduction

This study was undertaken to determine the water solubility of the test material. The method used was compatible with OECD Guideline 105 (Water Solubility).

Results & Conclusions

The water solubility of the test material was determined to be 3.2 mg/L in this study. Therefore the test material is slightly soluble in water.