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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
April 12, 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
other: visual observation
Deviations:
no
GLP compliance:
yes
Key result
Medium:
ethanol
Solubility:
> 1 g/L
Temp.:
21 °C
Key result
Medium:
acetone
Solubility:
> 1 g/L
Temp.:
21 °C
Key result
Medium:
other: hexane
Solubility:
> 1 g/L
Temp.:
21 °C
Conclusions:
Under the study conditions, the test substance solubility was above 1 g/L for ethanol, acetonitrile and hexane.
Executive summary:

A study was conducted to determine solubility of the test substance in organic solvents by visual observations. This test was only performed to give an approximate range of solubility of the test substance in different organic solvents. It does not raise the claim to determine exact solubility in g/L. Under the study conditions, the test substance solubility was above 1 g/L for ethanol, acetonitrile and hexane (Stannek, 2017).

Description of key information

The solubility in organic solvents was determined by dissolving different amounts of the test substance in three organic solvents (Stannek, 2017).

Key value for chemical safety assessment

Solubility in organic solvents at 20°C:
1 g/L

Additional information

>1 g/L in ethanol, acetonitrile and hexane