Registration Dossier

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information


One study in 2018 shows positive to tester strains TA1537, TA98, TA100 and WP2uvrA in the absence of S9-mix, and the results were reproducible in a follow up experiment, these increases are considered to be biologically relevant and the test item is considered to be mutagenic.

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (positive)

Additional information

Justification for classification or non-classification

Positive result in Ames study.

Therefore in accordance with Regulation (EC) No. 1272/2008 Table 3.5.1, this substance should be classified as a Category 2 mutagen.