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EC number: 609-463-9
CAS number: 376653-41-7
Acute toxicity: oral
LD50 > 2000 mg/kg bw in
female CRL:(WI) rats.
Acute Toxicity: oral
Initially, three females
(Group 1) were treated at a dose level of 2000 mg/kg bw.
As no mortality was observed
in group 1 a second group (Group 2) of 3 animals was treated at the same
dose level as for Group 1.
did not cause mortality at a dose level of 2000 mg/kg bw.
Clinical Observations: Treatment
with BAL0001026 at the dose level of 2000 mg/kg bw did not cause any
adverse clinical signs.
Body Weight and Body Weight
Gain: There were no
treatment related effects on body weight or body weight gain during the
Macroscopic Findings: There
was no evidence of treatment-related macroscopic changes at necropsy in
animals given 2000 mg/kg bw.
the absence of any acute toxicity, BAL0001026 can be ranked as "Category
5" or "Unclassified" for acute oral toxicity according to the GHS
criteria. Although this study was not designed to determine the acute
oral LD50, under the conditions of this study, it is assumed for
BAL0001026 to be above 2000 mg/kg bw in female CRL:(WI) rats.
In the absence of any acute
toxicity, BAL0001026 can be ranked as "Category 5" or "Unclassified" for
acute oral toxicity according to the GHS criteria.
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