Registration Dossier

Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
1961
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: only summary available

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1961

Materials and methods

Principles of method if other than guideline:
not specified
GLP compliance:
no
Test type:
standard acute method

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat

Administration / exposure

Route of administration:
oral: unspecified
Doses:
200-3200 mg/kg
No. of animals per sex per dose:
10 animals

Results and discussion

Effect levels
Dose descriptor:
LD50
Effect level:
3 200 mg/kg bw
Clinical signs:
Slight to very weak, slight to severe constant tremor, diarrhea, excessive lacrimation, "bloody tears", rough coat.

Applicant's summary and conclusion

Interpretation of results:
Category 5 based on GHS criteria