Registration Dossier
Registration Dossier
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EC number: 239-635-5 | CAS number: 15578-26-4
Acute Toxicity: dermal
Administrative data
- Endpoint:
- acute toxicity: dermal
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- N.N.
- Author:
- N.N.
- Year:
- 1 972
- Bibliographic source:
- National Technical Information Service. Vol. OTS0555171,
- Reference Type:
- publication
- Title:
- Can Acute Dermal Systemic Toxicity Tests Be Replaced With Oral Tests? A Comparison of Route-Specific Systemic Toxicity and Hazard Classifications Under the Globally Harmonized System of Classification and Labelling of Chemicals (GHS)
- Author:
- Nigel et all
- Year:
- 2 013
- Bibliographic source:
- Regulatory Toxicology and Pharmacology, 66(1), 30-37.
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- no guideline identified in National Technical Information Service. Vol. OTS0555171
- GLP compliance:
- no
- Test type:
- other: other unknown
- Limit test:
- no
Test material
- Reference substance name:
- Ditin pyrophosphate
- EC Number:
- 239-635-5
- EC Name:
- Ditin pyrophosphate
- Cas Number:
- 15578-26-4
- Molecular formula:
- H4O7P2.2Sn
- IUPAC Name:
- ditin pyrophosphate
- Test material form:
- solid
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Type of coverage:
- other: not relevant
- Vehicle:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 3 850 mg/kg bw
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Oral LD50 = 3850, so the dose for dermal toxicity is also higher than 2000 mg/kg bw
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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