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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Experimental starting date: 04 October 2017. Experimental completion date: 07 November 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
column elution method
Specific details on test material used for the study:
Identification: 2,2'-[propane-1,3-diylbis(oxy)]bis(3",5,5"-tri-tert-butyl-5'-methyl-1,1':3',1"-terphenyl-2’-ol)
Appearance/physical state: white powder
Batch: 1502501005
Purity: 98.1%
Expiry date: 01 February 2025
Storage conditions: room temperature, in the dark
Water solubility:
< 0 g/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
>= 5.8 - <= 6.8
Details on results:
Preliminary Test
The preliminary estimate of water solubility was ≤1.3 x 10-4 g/L at 20 °C.

Validation
The linearity of the detector response with respect to concentration was assessed over the nominal concentration range of 0.01 to 1.00 mg/L. The results were satisfactory with a first order correlation coefficient (r) of 0.9997 being obtained.

Discussion
As the water solubility was determined during the preliminary test to be below 1 x 10^-2 g/L and the test item was a solid, the column elution method was performed.
As no test item peak was detectable in the definitive test sample solutions, a limit value has been reported for the water solubility of the test item. The limit value reported originated from the nominal standard solution concentration (5.0 x 10^-5 g/L) used for analysis of the definitive test sample solutions, corrected for the dilution factor (2).

The concentration (g/L) of test item in the sample solutions is shown in the following table:

Sample Number

Sampling Time (hour)

Concentration (g/L)

Solution pH

System A

System B

System A

System B

System A

System B

1

94

94

<1.0 x 10-4

<1.0 x 10-4

6.3

6.6

2

117¾

117¾

<1.0 x 10-4

<1.0 x 10-4

6.8

6.7

3

142

142

<1.0 x 10-4

<1.0 x 10-4

6.2

6.5

4

164½

164½

<1.0 x 10-4

<1.0 x 10-4

6.3

6.3

5

189¾

189¾

<1.0 x 10-4

<1.0 x 10-4

5.8

6.1

The overall results are shown in the following table:

Determination

Concentration (g/L)

A

<1.0 x 10-4

B

<1.0 x 10-4

Overall result:            Less than1.0 x 10-4g/L at 20 °C

Conclusions:
The water solubility of the test item has been determined to be less than 1.0 x 10^-4 g/L of solution at 20.0 ± 0.5 °C.
Executive summary:

Water Solubility. Less than 1.0 x 10^-4 g/L of solution at 20.0 ± 0.5 °C, determined using a column elution method designed to be compatible with Method A.6 Water Solubility of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 105 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

Description of key information

The water solubility of the test item has been determined to be less than 1.0 x 10^-4 g/L of solution at 20.0 ± 0.5 °C.

Key value for chemical safety assessment

Additional information