Registration Dossier

Administrative data

Endpoint:
acute toxicity: inhalation
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
other:

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion

Executive summary:

The substance has very low vapor pressure (< 0.1 Pa at 25 °C), so the potential for the generation of inhalable forms is low, also the use of this substance will not result in aerosols, particles or droplets of an inhalable size, so exposure to humans via the inhalatory route will be unlikely to occur. Furthermore rhe results of laboratory animal studies show low acute oral and dermal toxicity for the related substance Tri (hexyl, octyl, decyl) ester. This intrinsic property/toxicity potential can be extrapolated to acute inhalative route administration.