Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 439-750-2 | CAS number: 183487-56-1
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 06-22 August 2001
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 002
- Report date:
- 2002
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- flask method
Test material
- Reference substance name:
- -
- EC Number:
- 439-750-2
- EC Name:
- -
- Cas Number:
- 183487-56-1
- Molecular formula:
- Hill formula: C17H19BrClNO3 CAS formula: C17H19BrClNO3
- IUPAC Name:
- (4aR*,8aR*)-1-bromo-4a,5,9,10,11,12- hexahydro-3-methoxy-11-methyl-6H-ben zofuro[3a,3,2-ef][2]benzazepin-6-one hydrochloride
- Test material form:
- solid: particulate/powder
Constituent 1
- Specific details on test material used for the study:
- - Batch n°: RT002113G3A231
- Analytical purity: 92.9%
- Expiration date: 01 December 2001
- Storage condition: at room temperature
Results and discussion
Water solubility
- Key result
- Water solubility:
- 207.9 g/L
- Conc. based on:
- test mat. (dissolved fraction)
- Loading of aqueous phase:
- 400 g/L
- Incubation duration:
- >= 24 - <= 72 h
- Temp.:
- 20 °C
- Remarks on result:
- other: standard deviation +/-9.7g/L
- Details on results:
- The water solubility was not corrected for the purity of the test item.
Any other information on results incl. tables
| Sample No. | Shaking time at 30°C | Concentration analysed (mg/L) | Concentration calculated (g/L) |
| 1 | 72 | 84.16 | 210.40 |
| 2 | 81.57 | 203.92 | |
| 3 | 48 | 78.89 | 197.24 |
| 4 | 79.29 | 198.21 | |
| 5 | 24 | 87.23 | 218.08 |
| 6 | 87.77 | 219.42 |
From these results a rounded value of 207.88 g/L was calculated . Standard deviation +/- 9.65 g/L
The measured results differed by less than 15%. Therefore, the study is considered to be valid.
Applicant's summary and conclusion
- Conclusions:
- The water solubility of T002113 was determined by the flask method to be 207.9 g/L at 20°C +/- 0.5°C. T002113 is very soluble.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
