Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Administrative data

Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Study period:
January 2018
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2018
Report Date:
2018

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 301 F (Ready Biodegradability: Manometric Respirometry Test)
Deviations:
no
GLP compliance:
yes (incl. certificate)

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
impurity
Test material form:
liquid

Study design

Oxygen conditions:
aerobic
Inoculum or test system:
activated sludge, domestic (adaptation not specified)
Duration of test (contact time):
28 d

Results and discussion

% Degradation
Key result
Parameter:
% degradation (O2 consumption)
Value:
76
Sampling time:
28 d

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Interpretation of results:
readily biodegradable
Executive summary:

The Ready Biodegradability of Homofarnesol (3E, 7E) was determined by the Manometric Respirometry Test.

Homofarnesol (3E, 7E) undergoes 76% biodegradation after 28 days in the test conditions. The 10 -day window criterion is also fulfilld (27% biodegradation on day 3 and 67% on day 13).

At the test concentration, Homofarnesol (3E, 7E) did inhibit the intrinsic respiration of the inoculum by more than 20% on the first day of the test. Toxicity towards the inoculum cannot therefore be excluded.

Homofarnesol (3E, 7E) should be regarded as readily biodegradable according to this test.