Registration Dossier
Registration Dossier
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EC number: 207-987-9 | CAS number: 504-24-5
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 2 017
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- Peer reviewed summary from US EPA
- GLP compliance:
- not specified
- Remarks:
- data from a reliable peer reviewed summary from US EPA
- Test type:
- other: Acute dermal
- Limit test:
- no
Test material
- Reference substance name:
- 4-pyridylamine
- EC Number:
- 207-987-9
- EC Name:
- 4-pyridylamine
- Cas Number:
- 504-24-5
- Molecular formula:
- C5H6N2
- IUPAC Name:
- nickel
- Test material form:
- solid: particulate/powder
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation: dust
- Type of inhalation exposure:
- not specified
- Vehicle:
- not specified
- Analytical verification of test atmosphere concentrations:
- not specified
- Control animals:
- not specified
Results and discussion
Effect levels
- Key result
- Sex:
- not specified
- Dose descriptor:
- LC50
- Effect level:
- 0.53 mg/L air
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- Category 3 based on GHS criteria
- Conclusions:
- Acute inhalation LD50: 0.53 mg/L
- Executive summary:
Acute inhalation LD50: 0.53 mg/L
(toxicology review: EPA TSCA Inventory)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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