Registration Dossier
Registration Dossier
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EC number: 201-796-4 | CAS number: 88-09-5
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- Not available
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Insufficient information for an assessment of reliability.
- Principles of method if other than guideline:
- Not available
- GLP compliance:
- not specified
- Type of method:
- other: Not available
- Partition coefficient type:
- octanol-water
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.68
- Remarks on result:
- other: Additional information not available
- Conclusions:
- An octanol-water partition coefficient of Log Kow = 1.68 was determined for 2-ethylbutyric acid, suggesting that the registered substance is soluble in water (hydrophilic).
- Endpoint:
- partition coefficient
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- weight of evidence
- Study period:
- April 2018
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Results derived from a calculation method with limited documentation / justification.
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The octanol-water partition coefficient of 2-ethylbutyric acid was estimated in KOWWIN™ (Epi Suite) using the fragment constant method. The model assigns coefficient values to the individual fragments (atoms and functional groups) that constitute the molecule and these are summed to provide the Log Kow.
- GLP compliance:
- no
- Type of method:
- calculation method (fragments)
- Partition coefficient type:
- octanol-water
- Key result
- Type:
- log Pow
- Partition coefficient:
- 1.98
- Remarks on result:
- other: Additional information not available
- Conclusions:
- An octanol-water partition coefficient of Log Kow = 1.98 was estimated for 2-ethylbutyric acid, suggesting that the registered substance is soluble in water (hydrophilic).
Referenceopen allclose all
Description of key information
An octanol-water partition coefficient of Log Kow = 1.68 and 1.98 was identified for 2-ethylbutyric acid. The Log Kow of 1.68 has been recommended as the key value given that it is based on experimental data, while the latter was determined in a model calculation. 2-Ethylbutyric acid can be regarded as soluble in water (hydrophilic).
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 1.68
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
