Registration Dossier

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
oxidising properties, other
Type of information:
other: Expert assessment
Adequacy of study:
key study
Study period:
January 30, 2018
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An assessment was undertaken based on an examination of the molecular structure (functionality) of the substance and its minor constituents.
Qualifier:
no guideline followed
Principles of method if other than guideline:
An assessment was undertaken to determine the oxidising potential of 2-butoxyethyl methacrylate. This was achieved by reviewing the molecular structure (functionality) of the registered substance and its minor constituents and by referring to relevant regulation to develop a screening procedure, namely the Registration, Evaluation, Authorisation & Restriction of Chemicals (REACH) Regulation (EC) No 1907/2006 and the Classification, Labelling and Packaging (CLP) Regulation (EC) No 1272/2008.
GLP compliance:
no
Key result
Sample tested:
other: Expert assessment
Parameter:
other: Molecular structure (functionality)
Remarks on result:
other: 2-Butoxyethyl methacrylate is not expected to possess oxidising properties
Interpretation of results:
GHS criteria not met
Conclusions:
Based on an expert assessment of the molecular structure and functionality of 2-butoxyethyl methacrylate, it was concluded that the registered substance is not expected to possess oxidising properties. Classification as an oxidising agent is not required (CLP Regulation (EC) No 1272/2008).
Executive summary:

An expert assessment was performed to examine the molecular structure and functionality of 2-butoxyethyl methacrylate and its minor constituents: 2-butoxyethanol, ethylene dimethacrylate, butyl methacrylate, and 4-hydroxyanisole. The purpose of this evaluation was to determine whether 2-butoxyethyl methacrylate contained oxidising properties. The CLP Regulation (EC) No 1272/2008 and REACH Regulation (EC) No 1907/2006 were referred to in order to establish a screening procedure to assess oxidising potential. 2-Butoxyethyl methacrylate was found to contain three oxygen atoms. However, as these are securely bound to carbon the registered substance is not considered as conferring oxidising properties. Of the minor constituents, ethylene dimethacrylate and butyl methacrylate are structurally related to 2-butoxyethyl methacrylate and, therefore, do not contain chemical functionality associated with potential oxidising properties. 2-Butoxyethanol and 4-hydroxyanisole contain oxygen atoms that are bound to carbon and hydrogen and, therefore, they need not be considered as conferring oxidising properties. No constituent contains fluorine or chlorine atoms. It can be concluded that the registered substance, 2-butoxyethyl methacrylate, is not expected to possess oxidising properties and does not require classification as an oxidising agent (CLP Regulation (EC) No 1272/2008).

Description of key information

2-Butoxyethyl methacrylate and its minor constituents are not expected to exhibit oxidising behaviour based on an examination of potential functionality associated with oxidising properties. 2-Butoxyethyl methacrylate does not require classification as an oxidising agent (CLP Regulation (EC) No 1272/2008).

Key value for chemical safety assessment

Oxidising properties:
non oxidising

Additional information

The endpoint conclusion obtained for oxidising properties can be regarded as a key value for the purpose of classification and chemical safety assessment. A Klimisch score of 2 (reliable with restrictions) has been recommended given that the endpoint value was determined by expert assessment of a weight of evidence.

Justification for classification or non-classification