Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

The toxicity of the 1,4-Bis (4-hydroxy benzoyl) benzene to the freshwater flea Daphnia magna and to the freshwater green algae Raphidocelis subcapitata (formerly known as Pseudokirchneriella subcapitata), was investigated in GLP-compliant studies performed in accordance with OECD Guideline No. 202 and OECD Guideline No. 201 respectively. In addition, due to the low solubility of the test item in the test media, procedures were based on the test methods described in the OECD series on testing and assessment number 23 (2000).

 

Invertebrate:

Under the conditions of the study, no immobility was observed at any of the concentrations of 1,4-Bis (4-hydroxy benzoyl) benzene tested. The EC50 for immobilization (48h-EC50) for Daphnia magna was > 0.17 mg/L, measured concentration being considered to be the maximum soluble concentration of the test item in test medium at a loading rate of 100 mg/L.

 

Algae:

Under the conditions of the study, no inhibition of growth rate or inhibition of yield was recorded at any of the concentrations of 1,4-Bis (4-hydroxy benzoyl) benzene tested. The EC50 for growth rate inhibition (72h-ErC50) and the EC50 for yield inhibition (72h-EyC50) were > 0.16 m/L, measured concentration being considered to be the maximum solubility of the test item in test medium at a loading rate of 100 mg/L.

The 72h-NOEC for both growth rate and yield inhibition was ≥ 0.16 mg/L.

 

In conclusion, there was no toxicity below the limit of solubility in the test media. Therefore no classification is needed under the regulation EC 1272/2008.

Additional information