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Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Reference
Endpoint:
solubility in organic solvents / fat solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Insufficient documentation for an assessment of reliability.
GLP compliance:
not specified
Medium:
methanol
Solubility:
> 500 g/L
Temp.:
20 °C
Medium:
ethanol
Solubility:
> 500 g/L
Temp.:
20 °C
Medium:
isopropanol
Solubility:
> 500 g/L
Temp.:
20 °C
Medium:
other: dichloromethane
Solubility:
> 500 g/L
Temp.:
20 °C
Medium:
other: 2-propanone
Solubility:
> 500 g/L
Temp.:
20 °C
Medium:
dimethylformamide
Solubility:
> 500 g/L
Temp.:
20 °C
Conclusions:
The solubility of T000749 in different organic solvents (methanol, ethanol, isopropanol, DCM, DMF, etc.) was determined to be > 500.0 g/L at 20°C.

Description of key information

A K4 study reports various solubilities of test substance in different organic solvents (J&J PRD).

Key value for chemical safety assessment

Additional information

solvent  solubility g/L (20°C)
methanol  >500
ethanol >500
2-propanol  >500
dichloromethane  >500
2-propanone  >500
dimethylformamide >500