Registration Dossier

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
January 2003
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
test procedure in accordance with national standard methods with acceptable restrictions

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2011
Report date:
2011

Materials and methods

Test guideline
Qualifier:
equivalent or similar to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Principles of method if other than guideline:
Differential scanning calorimetry or DSC is a thermoanalytical technique in which the difference in the amount of heat required to increase the temperature of a sample and reference is measured as a function of temperature. Both the sample and reference are maintained at nearly the same temperature throughout the experiment.
GLP compliance:
not specified
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
-
EC Number:
423-370-9
EC Name:
-
Cas Number:
10097-09-3
Molecular formula:
C19H24N4O2
IUPAC Name:
1-[4-({4-[(dimethylcarbamoyl)amino]phenyl}methyl)phenyl]-3,3-dimethylurea
impurity 1
Reference substance name:
unknown
IUPAC Name:
unknown
impurity 2
Chemical structure
Reference substance name:
Water
EC Number:
231-791-2
EC Name:
Water
Cas Number:
7732-18-5
Molecular formula:
H2O
IUPAC Name:
Water
Test material form:
solid: bulk

Results and discussion

Melting / freezing point
Key result
Melting / freezing pt.:
>= 216 - <= 218 °C
Atm. press.:
ca. 1 013 hPa
Decomposition:
yes
Decomp. temp.:
>= 200 °C
Sublimation:
no

Any other information on results incl. tables

The melting point of MDI-Urone was determined applying DSC. 7.4 mg test substance were put into a platen and heated up to 300°C. The onset (216°C) and the peak (218°C) of the endothermic heat fluxes were measured. The melting point is reported as the peak of the endothermic heat fluxes.

Applicant's summary and conclusion

Conclusions:
The melting point of MDI-Urone is 216-218°C.
Executive summary:

The melting point of MDI-Urone was determined applying differential scanning calorimetry. The test protocol is equivalent to the guideline EU A.01. The test substance, 7.4 mg TDI-Urone, were put into a platen at room temperature and heated up to 300°C. The onset and the peak of the endothermic heat fluxes were reported. The onset of the endothermic heat flux is 216°C and reaches a peak at 218°C. According the guideline EU A.01 the melting point is the temperature at which the final stage of melting is reached. Therefore, the melting point of TDI-Urone is 216 -218°C.