(Z)-N-[2-(2-hydroxyethoxy)ethyl]-9-octadecenamide

Melting point / freezing point

Link to relevant study record(s)

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From June 12, 2017 to September 20, 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

2008

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Version / remarks:

1998

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

>= 9 - <= 29.4 °C

Decomposition:

yes

Decomp. temp.:

> 50 °C

TGA EXPERIMENT (PRELIMINARY TEST)

Starting at 100°C, the weight of the sample decreased significantly: 25% weight loss at 316°C and 70% weight loss at 440°C.

After the experiment, a dark brown molten residue remained in the sample container. The change of the colour indicated reaction and/or decomposition of the test substance.

 

DSC EXPERIMENT 1

During cooling two exothermic peaks were observed between 25°C and -25°C, most probably due to crystallisation of the test substance. During heating three endothermic peaks were observed between -25°C and 50°C directly followed by a broad endothermic effect starting at 50°C. The peak max temperature of the first peak was 9.329°C and of the last peak was 29.370°C. The endothermic effects were most likely obtained due to melting of the test substance. After the experiment, a light yellow molten residue remained in the sample container. 

DSC EXPERIMENT 2

In order to investigate whether reaction and/or decomposition of the test substance did already occur during melting, Experiment 2 was stopped at 50°C. Again, endothermic peaks were observed between -25°C and 50°C. The peak max temperature of the first peak was 8.979°C and of the last peak was 19.627°C. After the experiment, an off-white molten residue remained in the sample container. It demonstrated that melting was the reason for the endothermic effect and that reaction and/or decomposition of the test substance did not occur at temperatures up to 50°C. 

DATA HANDLING

The melting temperature was determined as a melting range obtained from the lowest peak max of the first melting temperature (9.0°C) and the highest peak max of the last melting temperature (29.4°C).

Conclusions:

Under the study conditions, from duplicate experiments, the melting range was established between 9.0°C and 29.4°C. Reaction and/or decomposition of the substance occurs at temperatures above 50°C.

Executive summary:

A study was conducted to determine the melting point of the test substance according to OECD 102 Guideline, EU Method A.1 and OPPTS 830.7200. A melting range instead of a well defined melting temperature was determined. Under the study conditions, from duplicate experiments, the melting range was established between 9.0°C and 29.4°C. Reaction and/or decomposition of the substance occurs at temperatures above 50°C (Reingruber, 2017).

Description of key information

The melting point was determined according to OECD Guideline 102, EU Method A.1 and OPPTS 830.7200 (Reingruber, 2017).

Additional information

The melting range: 9.0°C - 29.4°C. Reaction and/or decomposition: >50°C.