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Physical & Chemical properties

Water solubility

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
06 Jan - 13 Jan 2017
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Reference:
Composition 0
Qualifier:
according to
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
adopted in 1995
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
adopted in 2008
Deviations:
no
GLP compliance:
no
Type of method:
flask method
Test material information:
Composition 1
Specific details on test material used for the study:
Storage conditions: ambient temperature (10 to 30 °C)
Water solubility:
ca. 77 g/L
Conc. based on:
test mat. (dissolved fraction)
Temp.:
20 °C
Remarks on result:
other: pH at 23 - 24 °C was 2.2

Results
Table 1 – Preliminary Test Results

Amount of test item [mg]

Added volume of distilled water [mL]

Total volume [mL]

Appearance of mixture

108.4

0.1

0.1

Not dissolved

0.4

0.5

0.5

1.0

1.0

2

dissolved

 

From the preliminary tests, the water solubility is > 10 mg/L. In the main test, water solubility was determined with the flask method.

After the equilibration time, precipitate was seen in the flaks with the exception of the blank experiment. Water solubility was calculated from measured unrounded concentration values and not from rounded values.

Table 3 – Test item water solubility

Experiment

24 h experiment

48 h experiment

72 h experiment

Blank experiment

Amount of test item [g]

5.75

5.94

5.81

--

Amount of distilled water [mL]

10

Stirring time at 30 °C [h]

24

48

72

72

pH at 23 – 24 °C

2.2

5.4

Dilution factor

800

Measured concentration [mg/L]

97.81
97.78

95.74
95.75

95.07
94.99

--
--

Mean concentration [mg/L]

97.79

95.75

95.03

--

Water solubility [g/L]

78.2

76.6

76.0

--

 

The mean water solubility of the test item at 20 °C was determined to be: cs= 77 g/L (±1 g/L).

Description of key information

77 g/L (± 1 g/L) at 20 °C (OECD 105, Flask method)

Key value for chemical safety assessment

Water solubility:
77 g/L
at the temperature of:
20 °C

Additional information