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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Sep 25, 1982
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Remarks:
No pH and exact temperature values are given.
Reference:
Composition 0
Principles of method if other than guideline:
HPLC method
GLP compliance:
no
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Test material information:
Composition 1
Type:
log Pow
Partition coefficient:
7.25
Remarks on result:
other: no pH ist availiable, estimated value.
Details on results:
No exact temperature is given in the report.

Results

Regression line of standard substances

 

Table.1 R.t.(min) and Log po/w of standard substances

Standard substance

R.t.(min) *1

Log Pow *2

benzyl alcohol

4.72

1.10

Benzene

6.15

2.13

Bromobenzene

7.42

2.99

Biphenyl

9.82

3.76

di-benzyl

12.28

4.81

p,p’-DDT

17.35

6.19

       *1 refer to chromatogram of standard substance

  *2 reference value, references,

G.D. Veith, N.M.Austin, R.T.Morris(1978) A Rapid Method for Estimating LogP for Organic Chemicals, Water Research vol. 13. Pp43 to 47.

    (1) Log Pow=-4.89 + 8.90 log R.T. (r2=0.997)

 

Test substance:

 R.T. = 23.14 min (form chromatogram)

 Log Pow = 7.25 (from (1))

Description of key information

log Pow = 7.25 (estimated value from column elution method), no pH and exact temperature values are given.

Key value for chemical safety assessment

Additional information