trans-cinnamic acid

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

The study was conducted between 07 and 11 June 2018/

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2018

Report date:

2018

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

OECD Guideline 104 (Vapour Pressure Curve)

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

EU Method A.4 (Vapour Pressure)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Remarks:

Date of Inspection: 18/07/2017-20/07/2017 Date of Issue: 28/11/2017

Type of method:

effusion method: vapour pressure balance

Test material

Test material information

Constituent 1

Reference substance name:

trans-cinnamic acid

EC Number:

205-398-1

EC Name:

trans-cinnamic acid

Cas Number:

140-10-3

Molecular formula:

C9H8O2

IUPAC Name:

3-phenylacrylic acid

Test material form:

solid: particulate/powder

Specific details on test material used for the study:

SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: 20171106
- Expiration date of the lot/batch: 10 April 2020
- Purity test date: 99.4%



STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material: Room temperature, over silica gel in the dark

Results and discussion

Vapour pressure

Key result

Test no.:

#1

Temp.:

25 °C

Vapour pressure:

< 0.003 Pa

Any other information on results incl. tables

Recorded temperatures, mass differences and the resulting calculated values of vapour pressure are shown in the following tables:

Table 1 – Vapour Pressure Data (Run 7)

 

Temperature (ºC)	Temperature (K)	Reciprocal Temperature (K-1)	Mass Difference (μg)	Mass Difference (kg)	Vapor Pressure (Pa)	Log10Vp
50	323.15	0.003095	4.59	4.590e-09	0.00637	-2.19586
51	324.15	0.003085	2.30	2.300e-09	0.00319	-2.49621
52	325.15	0.003076	3.19	3.190e-09	0.00443	-2.35360
53	326.15	0.003066	2.80	2.800e-09	0.00389	-2.41005
54	327.15	0.003057	3.49	3.490e-09	0.00485	-2.31426
55	328.15	0.003047	3.00	3.000e-09	0.00416	-2.38091
56	329.15	0.003038	2.40	2.400e-09	0.00333	-2.47756
57	330.15	0.003029	3.19	3.190e-09	0.00443	-2.35360
58	331.15	0.003020	3.49	3.490e-09	0.00485	-2.31426
59	332.15	0.003011	3.19	3.190e-09	0.00443	-2.35360
60	333.15	0.003002	2.90	2.900e-09	0.00403	-2.39469

 

No statistical analysis is given due to the nature of the plot.

 

Table 2 – Vapour Pressure Data (Run 8)

 

Temperature (ºC)	Temperature (K)	Reciprocal Temperature (K-1)	Mass Difference (μg)	Mass Difference (kg)	Vapor Pressure (Pa)	Log10Vp
50	323.15	0.003095	3.49	3.490e-09	0.00485	-2.31426
51	324.15	0.003085	2.00	2.000e-09	0.00278	-2.55596
52	325.15	0.003076	2.60	2.600e-09	0.00361	-2.44249
53	326.15	0.003066	2.70	2.700e-09	0.00375	-2.42597
54	327.15	0.003057	4.09	4.090e-09	0.00568	-2.24565
55	328.15	0.003047	3.00	3.000e-09	0.00416	-2.38091
56	329.15	0.003038	4.89	4.890e-09	0.00679	-2.16813
57	330.15	0.003029	6.09	6.090e-09	0.00845	-2.07314
58	331.15	0.003020	5.29	5.290e-09	0.00734	-2.13430
59	332.15	0.003011	4.99	4.990e-09	0.00693	-2.15927
60	333.15	0.003002	4.69	4.690e-09	0.00651	-2.18642

 

Table 3 – Vapour Pressure Data (Run 9)

 

Temperature (ºC)	Temperature (K)	Reciprocal Temperature (K-1)	Mass Difference (μg)	Mass Difference (kg)	Vapor Pressure (Pa)	Log10Vp
50	323.15	0.003095	2.60	2.600e-09	0.00361	-2.44249
51	324.15	0.003085	3.00	3.000e-09	0.00416	-2.38091
52	325.15	0.003076	3.99	3.990e-09	0.00554	-2.25649
53	326.15	0.003066	3.99	3.990e-09	0.00554	-2.25649
54	327.15	0.003057	2.70	2.700e-09	0.00375	-2.42597
55	328.15	0.003047	3.69	3.690e-09	0.00512	-2.29073
56	329.15	0.003038	3.29	3.290e-09	0.00457	-2.34008
57	330.15	0.003029	3.59	3.590e-09	0.00498	-2.30277
58	331.15	0.003020	5.09	5.090e-09	0.00707	-2.15058
59	332.15	0.003011	4.29	4.290e-09	0.00596	-2.22475
60	333.15	0.003002	3.49	3.490e-09	0.00485	-2.31426

 

Applicant's summary and conclusion

Conclusions:

The vapor pressure of the test item has been determined to be less than 2.8 x 10-3 Pa at 25 ºC.

Executive summary:

The vapor pressure of trans-cinnamic acid has been determined to be less than 2.8 x 10-3 Pa at 25 °C, using the vapor pressure balance method, designed to be compatible with Method A.4 Vapour Pressure of Commission Regulation (EC) No 440/2008 of 30 May 2008, and Method 104 of the OECD Guidelines for Testing of Chemicals, 23 March 2006.